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Kidney transplantation outcomes in patients with IgA nephropathy and other glomerular and non-glomerular primary diseases in the new era of immunosuppression.

Sophia LionakiIlias MakropoulosKonstantinos PanagiotellisGeorge VlachopanosIoannis GavalasSmaragdi MarinakiGeorge LiapisIoannis El MichelakisIoannis BokosIoannis Boletis
Published in: PloS one (2021)
Recipients with IgAN as primary disease, experienced outcomes comparable to those of recipients with other causes of ESKD. The rate of IgAN recurrence in the graft was significantly lower than the rate of FSGS recurrence, but higher than the one recorded in recipients with LN or PIGN. Tacrolimus, as part of the KTx maintenance therapy, was associated with lower rates of IgAN recurrence in the graft, compared to the rate cyclosporine.
Keyphrases
  • kidney transplantation
  • free survival
  • diabetic nephropathy
  • adipose tissue
  • skeletal muscle
  • metabolic syndrome
  • bone marrow
  • insulin resistance