Bronchoalveolar lavage fluid lymphocytosis in chronic hypersensitivity pneumonitis: a systematic review and meta-analysis.

Nicola AdderleyChristopher J HumphreysHayley BarnesBrett LeyZahra A PremjiKerri A Johannson

Published in: The European respiratory journal (2020)

BAL lymphocyte percentage is higher in CHP compared to IPF and other IIPs, with higher thresholds providing improved specificity at the cost of sensitivity. However, the parent studies are at risk of incorporation bias and prospective studies should evaluate the additive discriminate value of BAL lymphocyte percentage to accurately diagnose CHP.

Keyphrases

case control
peripheral blood
idiopathic pulmonary fibrosis
drug induced
rheumatoid arthritis
interstitial lung disease
systemic sclerosis
structural basis