Bacterial biofilms predominate in both acute and chronic human lung infections.
Mette KolpenKasper Nørskov KraghJuan Barraza EncisoDaniel Faurholt-JepsenBirgitte LindegaardGertrud Baunbæk EgelundAndreas Vestergaard JensenPernille RavnInger Hee Mabuza MathiesenAlexandra Gabriella GheorgeFrederik Boëtius HertzTavs QvistMarvin WhiteleyPeter Østrup JensenThomas BjarnsholtPublished in: Thorax (2022)
Our findings indicate that the current paradigm of equating planktonic with acute and biofilm with chronic infection needs to be revisited as the difference lies primarily in metabolic rates, not bacterial architecture.