Establishing pathological cut-offs of brain atrophy rates in multiple sclerosis.
Nicola De StefanoMaria Laura StromilloAntonio GiorgioMaria Letizia BartolozziMarco BattagliniMariella BaldiniEmilio PortaccioMaria Pia AmatoMaria Pia SormaniPublished in: Journal of neurology, neurosurgery, and psychiatry (2015)
Our evidence-based criteria provide values able to discriminate the presence or absence of 'pathological' brain volume loss in MS with high specificity. Such results could be of great value in a clinical setting, particularly in assessing treatment efficacy in MS.