Association of anemia and hemoglobin decrease during acute stroke treatment with infarct growth and clinical outcome.
Sebastian BellwaldRupashani BalasubramaniamMichael NaglerMeret S BurriSamuel D A FischerArsany HakimTomas DobrockyYannan YuFabien ScalzoMirjam R HeldnerRoland WiestMarie-Luise MonoHakan SarikyaMarwan El-KoussyPasquale MordasiniUrs FischerGerhard SchrothJan GrallaHeinrich P MattleMarcel ArnoldDavid LiebeskindSimon JungPublished in: PloS one (2018)
Anemia at hospital admission and any hemoglobin decrease during acute stroke treatment affect outcome negatively, probably by enlarging and accelerating infarct growth. Our results indicate that hemodilution has an adverse effect on penumbral evolution. Whether hemoglobin decrease in acute stroke could be avoided and whether this would improve outcome would need to be studied prospectively.