Cardiac Substructure Radiation Dose and Risk of Late Cardiac Disease in Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study.
James E BatesSuman ShresthaQi LiuSusan A SmithDaniel A MulrooneyWendy M LeisenringTodd M GibsonLeslie L RobisonEric J ChowKevin C OeffingerGregory T ArmstrongLouis S ConstineBradford S HoppeChoonsik LeeYutaka YasuiRebecca M HowellPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Among children with cancer, there may be no threshold dose below which radiation to the cardiac substructures does not increase the risk of cardiac diseases. This emphasizes their importance in modern treatment planning.