Comprehensive Analyses of Somatic Copy Number Alterations and Mutations Based on the Adenoma-Carcinoma Sequence.

Tamotsu SugaiMitsumasa OsakabeNoriyuki UesugiWataru HabanoNaoki YanagawaHiromu Suzuki

Published in: Genes, chromosomes & cancer (2024)

We suggest that considerable SCNAs and TP53 mutations are required for progression from adenoma to carcinoma within the same intramucosal neoplastic lesion.

Keyphrases

copy number
mitochondrial dna
genome wide
dna methylation
amino acid