Amisulpride decreases tau protein hyperphosphorylation in the brain of OXYS rats.
Camilla A MolobekovaElena M KondaurovaTatiana V IlchibaevaAlexander Ya RodnyyNatalia A StefanovaNataliya G KolosovaVladimir S NaumenkoPublished in: Current Alzheimer research (2023)
Thus, we propose amisulpride to have therapeutic potential against AD and that it can be the most effective in the early stages of the disease. We found that chronic administration of amisulpride could reduce pathological tau hyperphosphorylation while reducing anxiety.