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Monocentric evaluation of Ki-67 labeling index in combination with a modified RPA score as a prognostic factor for survival in IDH-wildtype glioblastoma patients treated with radiochemotherapy.

R DumkeC DumkeF EberleChristopher NimskyU KeberR Engenhart-CabillicS Lautenschläger
Published in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2022)
MGMT promoter methylation and Ki-67 labeling index were independent predictors of survival in our collective. We see further studies pooling patient collectives to reach larger patient numbers concerning Ki-67 labeling index as being warranted.
Keyphrases
  • prognostic factors
  • case report
  • neoadjuvant chemotherapy
  • dna methylation
  • gene expression
  • free survival
  • locally advanced
  • genome wide
  • squamous cell carcinoma
  • lymph node
  • high grade