Genetic analysis of hsCRP in American Indians: The Strong Heart Family Study.

Lyle G BestPoojitha BalakrishnanShelley A ColeKarin HaackJonathan M KocarnikNathan PankratzMatthew Zack AndersonNora FranceschiniBarbara V HowardElisa T LeeKari E NorthJason G UmansJoseph M YrachetaAna Navas-AcienV Saroja Voruganti

Published in: PloS one (2019)

In agreement with evidence from other populations, these data show CRP serum levels are under considerable genetic influence; and include loci, such as near CRP and other genes, that replicate results from other ethnic groups. These findings also suggest possible novel loci on chr 6 and other chromosomes that warrant further investigation.

Keyphrases

genome wide
dna methylation
genome wide association study
heart failure
copy number
big data
machine learning
data analysis
artificial intelligence