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The real-life outcome of pazopanib in patients with advanced soft tissue sarcoma: A retrospective cross-sectional study of a Turkish cohort.

Mustafa KaraağaçYasin SezginMelek Karakurt EryilmazMurat ArazMuhammet Ali KaplanMustafa Yıldırım
Published in: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners (2020)
We showed that pazopanib was well tolerated and had clinical benefit in patients with advanced soft tissue sarcoma in a Turkish cohort. This is the first study that suggests pazopanib-induced hypothyroidism may act as a predictive marker for better outcomes in patients with advanced soft tissue sarcoma.
Keyphrases
  • metastatic renal cell carcinoma
  • type diabetes
  • drug induced
  • adipose tissue
  • metabolic syndrome
  • replacement therapy
  • endothelial cells
  • weight loss
  • smoking cessation