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Zebrafish Galectin 3 binding protein is the target antigen of the microglial 4C4 monoclonal antibody.

Mireia RoviraMagali MiserocchiAlice MontanariLatifa HammouLaura ChometteJennifer PozoVirginie ImbaultXavier BisteauJulien Y Bertrand
Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2022)
The 4C4 monoclonal antibody recognizes Lgals3bpb, a predicted highly glycosylated protein whose function in the microglial lineage is currently unknown. Identification of Lgals3bpb as a new pan-microglia marker will be fundamental in forthcoming studies using the zebrafish model.
Keyphrases
  • monoclonal antibody
  • binding protein
  • inflammatory response
  • neuropathic pain
  • lipopolysaccharide induced
  • lps induced
  • spinal cord
  • spinal cord injury
  • case control
  • amino acid