Mitoquinone mesylate targets SARS-CoV-2 and associated lung inflammation through host pathways.

Anton PetcherskiMadhav SharmaMaria DaskouSandro SattaHariclea VasilopoulosCristelle HugoEleni RitouBarbara Jane DillonEileen FungGustavo GarciaClaudio ScafoglioArunima PurkayasthaBrigitte N GompertsGregory A FishbeinVaithilingaraja ArumugaswamiMarc LiesaOrian S ShirihaiTheodoros Kelesidis

Published in: bioRxiv : the preprint server for biology (2022)

Mitoquinone/mitoquinol mesylate has potent antiviral and anti-inflammatory activity in preclinical models of SARS-CoV-2 infection.

Keyphrases

sars cov
respiratory syndrome coronavirus
chronic myeloid leukemia
oxidative stress
coronavirus disease
cell therapy
anti inflammatory
stem cells
mesenchymal stem cells