Increased Intrathecal B and Plasma Cells in Patients With Anti-IgLON5 Disease: A Case Series.

Christine StrippelAnna HeidbrederAndreas Schulte-MecklenbeckLisanne KornTobias WarneckeNico MelzerHeinz WiendlMatthias PawlowskiCatharina C GrossStjepana Kovac

Published in: Neurology(R) neuroimmunology & neuroinflammation (2022)

Our findings indicate the importance of inflammatory mechanisms, in particular in early and acute anti-IgLON5 cases, which may support the use of immune-suppressive treatments in these cases. The main limitation of the study is the small number of cases due to the rarity of the disease.

Keyphrases

induced apoptosis
liver failure
oxidative stress
cell cycle arrest
respiratory failure
cell proliferation
cell death
drug induced
hepatitis b virus
endoplasmic reticulum stress
acute respiratory distress syndrome