Melatonin regulates oxidative stress and apoptosis in fetal hearts of pinealectomised RUPP rats.
Oguzhan DoganlarZeynep Banu DoğanlarMehmet Akif OvaliOrkut GüçlüUfuk DemirAyten DoğanMetehan UzunPublished in: Hypertension in pregnancy (2020)
Melatonin may be considered as a potential molecule for development of preventive strategies to reduce the PE induced risk of cardiovascular diseases in offspring.
Keyphrases
- oxidative stress
- diabetic rats
- cardiovascular disease
- high glucose
- induced apoptosis
- dna damage
- endoplasmic reticulum stress
- high fat diet
- ischemia reperfusion injury
- cell death
- cell cycle arrest
- drug induced
- signaling pathway
- endothelial cells
- skeletal muscle
- cell proliferation
- risk assessment
- insulin resistance
- cardiovascular events
- pi k akt
- heat shock protein
- heat stress