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Evidence for intrathecal sodium butyrate as a novel option for leptomeningeal metastasis.

Hidemitsu NakagawaYoshihiro YuiSatoru SasagawaKazuyuki Itoh
Published in: Journal of neuro-oncology (2018)
Continuous intrathecal SB administration significantly improved prognoses in a rat LM model, which suggests that SB is a promising therapy for LM.
Keyphrases
  • oxidative stress
  • cerebrospinal fluid
  • small cell lung cancer