Effect of serum panel reactive antibodies on allogeneic hematopoietic stem cell transplantation in pediatric thalassemia patients: A single-center experience.
Baris MalboraHakan SarbayZeynep DogusanAbdullah Avni AtayPublished in: Pediatric transplantation (2023)
Serum PRA in pediatric thalassemia patients may impact the outcomes of HSCT. PRA-positive patients had higher rates of blood product transfusion requirements. Although poor graft function, graft failure, and post-transplant complications were more common in the group 2, statistical significance was not observed. Identifying patients with high PRA levels can assist in optimizing transplant strategies and post-transplant care, leading to improved outcomes for the patients.
Keyphrases
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- healthcare
- peritoneal dialysis
- allogeneic hematopoietic stem cell transplantation
- type diabetes
- adipose tissue
- acute lymphoblastic leukemia
- patient reported outcomes
- palliative care
- risk factors
- young adults
- pain management
- affordable care act