A noninvasive method for the detection of foetal DNA in early pregnancy based on differential methylation pattern of Ras association domain family member 1A.

Yulin ShaWei LiuJiongzhi HongYan YangJian YuXiaodong Fu

Published in: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology (2024)

The detection of foetal cells in uterine cavity samples based on hypermethylation of RASSF1A and quantification of foetal cells can be used to prenatal screening. GATA-3 can be used to label EVTs.

Keyphrases

induced apoptosis
cell cycle arrest
loop mediated isothermal amplification
oxidative stress
transcription factor
endoplasmic reticulum stress
dna methylation
real time pcr
gene expression
signaling pathway
cell free
circulating tumor
sensitive detection