Dense core vesicle markers in CSF and cortical tissues of patients with Alzheimer's disease.
Neus BarrancoVirginia PláDaniel AlcoleaIrene Sánchez-DomínguezReiner Fischer-ColbrieIsidro FerrerAlberto LleóFernando AguadoPublished in: Translational neurodegeneration (2021)
These results demonstrate marked alterations of neuronal-specific prohormone convertases in CSF and cortical tissues of AD patients. The neuronal DCV cargos are biomarker candidates for synaptic dysfunction and neurodegeneration in AD.