Dense core vesicle markers in CSF and cortical tissues of patients with Alzheimer's disease.

Neus Barranco Virginia Plá Daniel Alcolea Irene Sánchez-DomínguezReiner Fischer-ColbrieIsidro Ferrer Alberto Lleó Fernando Aguado

Published in: Translational neurodegeneration (2021)

These results demonstrate marked alterations of neuronal-specific prohormone convertases in CSF and cortical tissues of AD patients. The neuronal DCV cargos are biomarker candidates for synaptic dysfunction and neurodegeneration in AD.

Keyphrases

end stage renal disease
gene expression
ejection fraction
chronic kidney disease
oxidative stress
cerebral ischemia
blood brain barrier
patient reported
mild cognitive impairment