ISSLS PRIZE IN BASIC SCIENCE 2018: Growth differentiation factor-6 attenuated pro-inflammatory molecular changes in the rabbit anular-puncture model and degenerated disc-induced pain generation in the rat xenograft radiculopathy model.

Shingo MiyazakiAshish D DiwanKenji KatoKevin ChengWon C BaeYang SunJunichi YamadaCarol MuehlemanMary E LenzNozomu InoueRobert L SahMamoru KawakamiKoichi Masuda

Published in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society (2018)

GDF6 injection may change the pathological status of degenerative discs and attenuate degenerated IVD-induced pain.

Keyphrases

chronic pain
high glucose
diabetic rats
pain management
neuropathic pain
public health
drug induced
oxidative stress
spinal cord
postoperative pain