Myocardial infarction drives trained immunity of monocytes, accelerating atherosclerosis.
Zheng DongLei HouWei LuoLi-Hong PanXiao LiHai-Peng TanRun-Da WuHao LuKang YaoMan-Di MuChen-Shan GaoXin-Yu WengJun-Bo GePublished in: European heart journal (2023)
The findings underscore the crucial role of monocyte trained immunity in accelerated atherosclerosis after MI, implying that SYK in blood classical monocytes may serve as a predictive factor for the progression of atherosclerosis in STEMI patients.