Validation Strategy for Ultrasensitive Mutation Detection.
Marija DebeljakMichael NoëStacy L RielLisa M HaleyAlexis L NorrisDerek A AndersonEmily M AdamsMasaya SuenagaKatie F BeierlMing-Tseh LinMichael G GogginsChristopher D GockeJames R EshlemanPublished in: Molecular diagnosis & therapy (2019)
The VAF correction was found to be more significant than haplotype correction. It is imperative that various technologies be evaluated against each other and laboratories be provided with defined quality control samples for proficiency testing.