A genetic variation in the CpG island of pseudogene GBAP1 promoter is associated with gastric cancer susceptibility.

Gaoxiang MaHanting LiuMulong DuGang ZhangYadi LinYuqiu GeMeilin Wang Guangfu JinQinghong ZhaoHaiyan ChuWeida GongZhengdong Zhang

Published in: Cancer (2019)

rs2990245 is significantly associated with a decreased risk of GC. Pseudogene GBAP1 contributes to the development and progression of GC by sequestering the miR-212-3p from binding to GBA.

Keyphrases

dna methylation
gas chromatography
gene expression
transcription factor
mass spectrometry
high resolution
liquid chromatography