The miR-199a-5p/HIF1α dual-regulatory axis participates in hypoxia-induced aggressive phenotypes of oral squamous cell carcinoma (OSCC) cells.

Xing ChenJianjun YuHao TianXu Cai

Published in: International journal of clinical oncology (2024)

miR-199a-5p and HIF1α form a dual-regulatory axis in OSCC cells; the miR-199a-5p/HIF1α dual-regulatory axis contributes to hypoxia-induced aggressive OSCC phenotypes.

Keyphrases

induced apoptosis
cell cycle arrest
transcription factor
endothelial cells
oxidative stress
cell death
signaling pathway
cell proliferation