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Physiologically Based Modelling Framework for Prediction of Pulmonary Pharmacokinetics of Antimicrobial Target Site Concentrations.

Linda B S AulinSebastian T TandarTorben van ZijpEtienne van BallegooiePiet H van der GraafMohammed A A SalehPyry VälitaloJohan G C van Hasselt
Published in: Clinical pharmacokinetics (2022)
The developed lung PBPK model framework constitutes a promising tool for characterization of pulmonary exposure of systemically administrated antimicrobials.
Keyphrases
  • pulmonary hypertension
  • staphylococcus aureus