The diagnostic benefit of 16S rDNA PCR examination of infective endocarditis heart valves: a cohort study of 146 surgical cases confirmed by histopathology.
Christina ArmstrongTim Christian KuhnMatthias DufnerPhilipp EhlermannStefan ZimmermannChristoph LichtensternJasmin SoethoffHugo A KatusFlorian LeuschnerAlexandra HeiningerPublished in: Clinical research in cardiology : official journal of the German Cardiac Society (2020)
S-440/2017 on 28.08.2017 retrospectively registered. Subdividing of all infective endocarditis patients in this study, showing that valve PCR yields valuable information for patients with skin commensals in blood cultures, which were either confirmed by the same detection in valve PCR or refuted by the detection of a different and typical pathogen in valve PCR. Additionally, benefit was determined in patients with negative or not available blood cultures and only positive detection in valve PCR. +: Positive; -: negative; n/a: not available results.
Keyphrases
- real time pcr
- aortic valve
- mitral valve
- aortic stenosis
- ejection fraction
- end stage renal disease
- transcatheter aortic valve replacement
- aortic valve replacement
- loop mediated isothermal amplification
- label free
- transcatheter aortic valve implantation
- chronic kidney disease
- heart failure
- newly diagnosed
- peritoneal dialysis
- coronary artery disease
- left ventricular
- wound healing