Synthetic soldiers: Turning T cells into immortal warriors.

Published in: The Journal of experimental medicine (2024)

The creation of synthetic T cell states has captivated the field of cell-based therapies. Wang et al. (https://doi.org/10.1084/jem.20232368) describe how disruption of BCOR and ZC3H12A unleashes anti-tumor T cells with unprecedented lifespan and killer instinct. Are we witnessing the birth of immortal super-soldiers in medicine?

Keyphrases

single cell
cell therapy
pregnant women
pregnancy outcomes
clear cell