InsT-ALLing CD7 chimeric antigen receptors before transplantation.
Julio DelgadoPublished in: British journal of haematology (2024)
In their paper, the authors present their experience with the use of chimeric antigen receptor T cells targeting CD7 as a bridge to allogeneic haematopoietic cell transplantation in patients with relapsed/refractory T-cell acute lymphoblastic leukaemia/lymphoblastic lymphoma. Commentary on: Cao et al. A safety and efficacy study of allogeneic haematopoietic stem cell transplantation for refractory and relapsed T-cell acute lymphoblastic leukaemia/lymphoblastic lymphoma patients who achieved complete remission after autologous CD7 chimeric antigen receptor T-cell therapy. Br J Haematol 2024;204:2351-2364.
Keyphrases
- cell therapy
- stem cell transplantation
- diffuse large b cell lymphoma
- high dose
- stem cells
- liver failure
- mesenchymal stem cells
- acute myeloid leukemia
- acute lymphoblastic leukemia
- respiratory failure
- multiple myeloma
- nk cells
- bone marrow
- hodgkin lymphoma
- drug induced
- aortic dissection
- intensive care unit
- hepatitis b virus
- cancer therapy
- acute respiratory distress syndrome