Salmon peptides limit obesity-associated metabolic disorders by modulating a gut-liver axis in vitamin D-deficient mice.

Marion VallePatricia L MitchellGeneviève PilonThibault VarinLoïc HénaultJonathan RolinRoger McLeodTom GillDenis RichardMarie-Claude VohlHélène JacquesClaudia GagnonLaurent BazinetAndré Marette

Published in: Obesity (Silver Spring, Md.) (2021)

SPF treatment improves MetS by modulating hepatic and gut inflammation along with gut microbiota, suggesting that SPF operates through a gut-liver axis. VitD3 supplementation has limited influence on MetS in this model.

Keyphrases

signaling pathway
metabolic syndrome
oxidative stress
type diabetes
insulin resistance
weight loss
weight gain
body mass index
skeletal muscle