Effect of Hydrotalcite on Indometacin-Induced Gastric Injury in Rats.

Yan Fei FangWen Li XuLan WangQing Wu LianLi Feng QiuHui ZhouShu-Jie Chen

Published in: BioMed research international (2019)

Hydrotalcite promotes gastric protection and healing via several mechanisms, including increased levels of PGE2 in blood serum, activation of EGF, and antagonising the inhibition of cyclooxygenase (COX) caused by NSAIDs.

Keyphrases

high glucose
diabetic rats
growth factor
oxidative stress
nitric oxide synthase
anti inflammatory drugs