Follicular Bronchiolitis: Two Cases with Varying Clinical and Radiological Presentation.
Delyse GargMohit ModyChaitanya PalPratik PatelChristina MiglioreChristine MinerowiczNikhil MadanPublished in: Case reports in pulmonology (2020)
Follicular bronchiolitis (FB) is a rare bronchiolar disorder associated with hyperplasia of the bronchial-associated lymphoid tissue (BALT). It is characterized by the development of lymphoid follicles with germinal centers in the walls of small airways. It falls under the category of lymphoproliferative pulmonary diseases (LPDs) and commonly occurs in relation to connective tissue disease, immunodeficiency, infections, interstitial lung disease (ILD), and inflammatory airway diseases. Computerized tomography (CT) findings include centrilobular nodules with patchy ground glass infiltrate, tree-in-bud findings, and air trapping. It can very rarely present as diffuse cystic lung disease. We present two cases of FB. The first case is associated with Human Immunodeficiency Virus (HIV) infection and asthma with diffuse cystic changes on the CT. The second case is associated with reactive airway disease and gastroesophageal reflux disease (GERD) with the classic centrilobular nodules and ground glass opacities on the CT.
Keyphrases
- interstitial lung disease
- human immunodeficiency virus
- systemic sclerosis
- image quality
- dual energy
- gastroesophageal reflux disease
- antiretroviral therapy
- computed tomography
- contrast enhanced
- hepatitis c virus
- rheumatoid arthritis
- idiopathic pulmonary fibrosis
- positron emission tomography
- low grade
- hiv infected
- pulmonary hypertension
- respiratory syncytial virus
- magnetic resonance imaging
- chronic obstructive pulmonary disease
- oxidative stress
- hiv aids
- magnetic resonance
- air pollution
- diffuse large b cell lymphoma
- electronic health record