Immunosuppressive therapy and humoral response to third mRNA COVID-19 vaccination with a six-month interval in rheumatic disease patients.
Yusuke KashiwadoYasutaka KimotoShiro OhshimaTakuya SawabeKensuke IrinoShota NakanoJunki HiuraAkiko YonekawaQiaolei WangGoro DoiMasahiro AyanoHiroki MitomaNobuyuki OnoYojiro ArinobuHiroaki NiiroTaeko HottaDongchon KangNobuyuki ShimonoKoichi AkashiTsutomu TakeuchiTakahiko HoriuchiPublished in: Rheumatology (Oxford, England) (2023)
Repeated vaccinations in many immunosuppressed patients produced antibody responses similar to those observed in HCs. In contrast, annual vaccination in patients receiving TNF inhibitors, abatacept, mycophenolate mofetil and rituximab may require caution.