Phthalates are detected in the follicular fluid of adolescents and oocyte donors with associated changes in the cumulus cell transcriptome.

Dilan Gokyer Mary J LawsAnna KleinhansJoan K RileyJodi A Flaws Elnur Babayev

Published in: bioRxiv : the preprint server for biology (2024)

Phthalates are detected in the follicular fluid of adolescents and oocytes donors, and the levels are increased in the follicular fluid of adolescents. Higher total phthalate levels in follicular fluid are associated with altered cumulus cells transcriptome in adolescents.

Keyphrases

young adults
physical activity
single cell
gene expression
rna seq
induced apoptosis
stem cells
cell cycle arrest
oxidative stress
cell death
cell proliferation
bone marrow