Anti-inflammatory and antiaging properties of chlorogenic acid on UV-induced fibroblast cell.

Ermi GirsangChrismis N GintingI Nyoman Ehrich ListerKamila Yashfa GunawanWahyu Widowati

Published in: PeerJ (2021)

CA has the potential as the protective compound against inflammation and aging by decreasing the level ROS, pro-inflammatory cytokines IL-1β and TNF-α, apoptotic cells, and necrotic cells and by increasing live cells and COL-3 gene expression.

Keyphrases

induced apoptosis
cell cycle arrest
gene expression
anti inflammatory
cell death
oxidative stress
endoplasmic reticulum stress
dna damage
dna methylation
mesenchymal stem cells
single cell
pi k akt
diabetic rats
protein kinase