Developing a rapid analytical method for simultaneous determination of apigenin and gallic acid: validation and application in a nanoliposomal formulation.
Ahmed GoudaOmar S SakrMaha NasrOmaima A SammourPublished in: Drug development and industrial pharmacy (2024)
The described HPLC method was shown to be suitable, sensitive, and reproducible for the simultaneous identification and quantification of apigenin and gallic acid. The analytical results were accurate and precise, with good recovery, low limit of detection, and the chromatographic assay was accomplished in less than 3 min, suggesting the suitability of the method for routine analysis of both drugs in pharmaceutical formulations.
Keyphrases
- simultaneous determination
- liquid chromatography
- liquid chromatography tandem mass spectrometry
- tandem mass spectrometry
- high performance liquid chromatography
- solid phase extraction
- ultra high performance liquid chromatography
- mass spectrometry
- loop mediated isothermal amplification
- ms ms
- drug delivery
- high resolution mass spectrometry
- gas chromatography