HLA-DQ2 homozygosis increases tTGA levels at diagnosis but does not influence the clinical phenotype of coeliac disease: A multicentre study.

Judit Bajor Péter Hegyi Márk Juhász Mária Papp Dorottya Kocsis Éva Szegedi Ildikó Földi Nelli Farkas Bálint Erőss Áron Vincze

Published in: International journal of immunogenetics (2019)

Our study shows a significant gene dose effect in terms of tTGA level at diagnosis, but no significant association between HLA-DQB1*02 allele dose and the clinical outcomes in CD.

Keyphrases

genome wide
copy number
gene expression
nk cells
genome wide analysis