Lower Lactate Levels and Lower Intracellular pH in Patients with IDH-Mutant versus Wild-Type Gliomas.

Katharina Johanna Wenger Joachim P Steinbach O Bähr U Pilatus Elke Hattingen

Published in: AJNR. American journal of neuroradiology (2020)

We found indirect evidence for metabolic reprogramming in IDH-mutant tumors with significantly lower lactate concentrations compared with IDH wild-type tumors and a near-normal intracellular pH.

Keyphrases

wild type
reactive oxygen species
high grade
low grade