Genetic polymorphisms and plasma concentrations of leptin (rs7799039) and adiponectin (rs17300539) are associated with obesity in children and adolescents.
Carlos Alberto MenezesEduardo Rodrigues Alves JuniorGustavo Nunes de Oliveira CostaThais Caroline Dallabona DombroskiRafael Teixeira de MattosJuliana de Assis Silva GomesFabricio Rios-SantosPublished in: Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo (2022)
The AG/AA polymorphisms in the leptin and adiponectin genes alter the serum levels of these adipokines and predispose them to obesity, and many anthropometric, biochemical, and hormonal markers are altered, demonstrating early consequences for the health of these obese children and adolescents.
Keyphrases
- metabolic syndrome
- insulin resistance
- weight loss
- adipose tissue
- type diabetes
- polycystic ovary syndrome
- high fat diet induced
- healthcare
- public health
- weight gain
- bariatric surgery
- body composition
- genome wide
- mental health
- skeletal muscle
- quantum dots
- highly efficient
- social media
- risk assessment
- human health
- body mass index
- genome wide analysis