Predicting cancer type from tumour DNA signatures.
Kee Pang SohEwa SzczurekThomas SakoparnigNiko BeerenwinkelPublished in: Genome medicine (2017)
A general cancer diagnostic tool that utilises either only somatic point mutations or only copy number alterations is not sufficient for distinguishing a broad range of cancer types. The combination of both gene alteration types can dramatically improve the performance.