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Predicting cancer type from tumour DNA signatures.

Kee Pang SohEwa SzczurekThomas SakoparnigNiko Beerenwinkel
Published in: Genome medicine (2017)
A general cancer diagnostic tool that utilises either only somatic point mutations or only copy number alterations is not sufficient for distinguishing a broad range of cancer types. The combination of both gene alteration types can dramatically improve the performance.
Keyphrases
  • copy number
  • papillary thyroid
  • mitochondrial dna
  • genome wide
  • squamous cell
  • dna methylation
  • gene expression
  • lymph node metastasis
  • squamous cell carcinoma
  • young adults