Low CD4 counts predict excessive weight gains during first-line treatment for HIV.
Andrew HillTamara Tovar SanchezEric DelaporteSimiso Mandisa SokhelaBryony SimmonsCharles KouanfackKaitlyn MccannJacob LeviCassandra FairheadWillem Daniel Francois VenterPublished in: The Journal of antimicrobial chemotherapy (2024)
Participants with low CD4 may demonstrate significant 'overshoot' weight gain, in addition to 'return to health', with a trend towards increased risk of obesity when initiated on TAF/FTC + DTG. Use of tenofovir disoproxil fumarate and efavirenz were associated with smaller weight gains. Effective weight management strategies are needed, especially for individuals with low baseline CD4.
Keyphrases
- weight gain
- body mass index
- birth weight
- antiretroviral therapy
- weight loss
- hiv infected
- healthcare
- hiv positive
- physical activity
- human immunodeficiency virus
- nk cells
- mental health
- hepatitis c virus
- hiv testing
- type diabetes
- metabolic syndrome
- hiv infected patients
- men who have sex with men
- health information
- peripheral blood
- social media
- preterm birth
- risk assessment