A novel experimental immunomodulatory therapy against Nocardia brasiliensis in a BALB/c murine model.

José Alberto García-LozanoC C García-BerlangaR T Viveros-RosadoJorge Ocampo CandianiJ Vargas-VillarrealLucio Vera-Cabrera

Published in: Clinical and experimental dermatology (2020)

In this experimental evaluation of an immunomodulatory therapy with attenuated N. brasiliensis strains in a murine model, there was a greater stability in the size of the lesion over time in BALB/c mice inoculated with the P400 strain. This treatment could open the possibility of using the attenuated strain as immunomodulatory therapy in patients recalcitrant to standard therapy, with high risk of dissemination or who develop drug-related adverse effects.

Keyphrases

escherichia coli
minimally invasive
type diabetes
cell therapy
drug induced