Network signatures define consciousness state during focal seizures.
Derek J DossGraham W JohnsonGhassan S MakhoulRohan V RashingkarJared S ShlessCamden E BibroDanika L PauloAbhijeet GummadavelliTyler J BallShilpa B ReddyRobert P NaftelKevin F HaasBenoit M DawantChristos ConstantinidisShawniqua Williams RobersonSarah K B BickVictoria L MorganDario J EnglotPublished in: Epilepsia (2024)
This study provides novel insights into ictal network measures in FASs, FIASs, and FBTCSs. Importantly, although both FIASs and FBTCSs result in loss of consciousness, our results suggest that ictal network changes in FIASs uniquely resemble those that occur during deep sleep. Our results may inform novel neuromodulation strategies for preservation of consciousness in epilepsy.