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Evaluation of a novel 177 Lu-labelled therapeutic Affibody molecule with a deimmunized ABD domain and improved biodistribution profile.

Yongsheng LiuMaryam OroujeniYunqi LiaoAnzhelika VorobyevaVitalina BodenkoAnna OrlovaMark KonijnenbergMatilda CarlqvistElisabet WahlbergAnnika LofteniusFredrik Y FrejdVladimir Tolmachev
Published in: European journal of nuclear medicine and molecular imaging (2024)
Lu]Lu-PEP49989 demonstrated favourable biodistribution and a strong antitumour effect, which was further enhanced by co-treatment with trastuzumab.
Keyphrases
  • pet imaging
  • epidermal growth factor receptor
  • computed tomography
  • positron emission tomography