The use of eculizumab in gemcitabine induced thrombotic microangiopathy.
Vinod KrishnappaMohit GuptaHaikoo ShahAbhijit DasNatthavat TanphaichitrRobert NovakRupesh RainaPublished in: BMC nephrology (2018)
Chemotherapy induced TMA is very rare and requires a high index of clinical suspicion for timely diagnosis. Discontinuation of the offending drug and supportive care is the main stay of treatment; however, eculizumab has been shown to be beneficial in GiTMA. Further research is required to validate this approach.