Pharmacogenetics of tamoxifen therapy in Asian populations: from genetic polymorphism to clinical outcomes.

Tingyu WangYitian ZhouGuosheng Cao

Published in: European journal of clinical pharmacology (2021)

This review revealed more systematic pharmacogenomics of genes involved in the metabolism and transport besides CYP2D6, are required to optimize the genotyping strategies and guide the personalized tamoxifen therapy in Asian populations.

Keyphrases

genome wide
genetic diversity
positive breast cancer
dna methylation
gene expression
adverse drug