The Protective Effect of Total Flavones from Rhododendron simsii Planch. on Myocardial Ischemia/Reperfusion Injury and Its Underlying Mechanism.

Sheng-Yong LuoQing-Hua XuGong Peng Zhi-Wu Chen

Published in: Evidence-based complementary and alternative medicine : eCAM (2018)

The results indicate that the protective effect of TFR on I/R injury may be correlated with its blocking UTR and the subsequent inhibition of RhoA/ROCK signaling pathway.

Keyphrases

ischemia reperfusion injury
signaling pathway
oxidative stress
pi k akt
left ventricular
epithelial mesenchymal transition
induced apoptosis
heart failure
atrial fibrillation