Serum Cortisol Assay Performance Following the 1 mg Overnight Dexamethasone Suppression Test.

Jonathan Shaun AtkinsJames M HawleyLaura J OwenJonathan Christopher ClaytonJonathan ScargillBrian G Keevil

Published in: Annals of clinical biochemistry (2023)

Clinicians should be aware of the method-dependent variation that exists within serum cortisol analysis during the ONDSTs. Roche and Siemens aligned more closely with LC-MS/MS while the Abbot may cause a reduction in ONDST sensitivity. This data supports assay-specific cut-offs for the ONDST.

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