Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development.

Joaquím Grego-BessaPaula Gómez-ApiñanizBelén PradosManuel J Jose Gómez Donal MacGrogan José Luis de la Pompa

Published in: Circulation research (2023)

These data establish the Nrg1-ErbB2/ErbB4 (erb-b2 receptor tyrosine kinase 4)-pErk axis as a crucial regulator of cardiomyocyte cell cycle progression and migration during ventricular development.

Keyphrases

cell cycle
tyrosine kinase
cell proliferation
epidermal growth factor receptor
heart failure
left ventricular
angiotensin ii
transcription factor
electronic health record
endoplasmic reticulum stress
endothelial cells
machine learning
atrial fibrillation