Serum neurofilament light chain level as a predictor of cognitive stage transition.

Eun-Hye LeeHyuk Sung KwonSeong-Ho KohSeong Hye ChoiJeong-Hwa JinJee Hyang JeongJae-Won JangKyung Won ParkEun-Joo KimHee Jin KimJin Yong HongSoo Jin YoonBora YoonJu-Hee KangJong-Min LeeHyun-Hee ParkJungsoon Ha

Published in: Alzheimer's research & therapy (2022)

The study shows that higher serum NFL tertile levels correlate with increased risk of cognitive stage transition in both MCI and CU participants. Serum NFL levels were negatively correlated with the mean cortical thickness of the whole-brain and specific brain regions.

Keyphrases

white matter
resting state
optical coherence tomography
multiple sclerosis
subarachnoid hemorrhage