Perinatal hepatitis B virus transmission in Lao PDR: A prospective cohort study.
Vatthanaphone LatthaphasavangPhilippe VanhemsNicole Ngo-Giang-HuongPhilavanh SibounlangPhimpha PaboribouneLaurent MalatoValy KeoluangkhotSyvilay ThammasackNicolas SalvadoriWoottichai KhamduangNicolas SteenkesteChristian TrépoPaul DényGonzague JourdainPublished in: PloS one (2019)
Mother-to-child transmission occurred less frequently than expected without the use of HBIg. Adding HBIg and/or maternal antiviral prophylaxis may have prevented some of these infections. The observation of unsatisfactory levels of anti-HBs antibodies in 9% of the uninfected infants at 6 months highlights the need for improvement of the universal immunization procedures.